Every effort should be made to submit a complete, intact application, including letters of support. Applicants have an obligation to check the submitted version of their grant applications to ensure completeness and correctness, and are provided a two business day application reviewing window to check the assembled application image in the NIH eRA Commons. During the initial peer review phase, acceptance of additional materials is at the discretion of the NLM Scientific Review Officer (SRO). Applicants should contact the SRO if they wish to submit additional materials before peer review. NIH policy on Submission of Additional Grant Application Materials can be found here.